Properties and Modeling of GWAS when Complex Disease Risk Is Due to Non-Complementing, Deleterious Mutations in Genes of Large Effect

Open Access

Peer-reviewed

Research Article

Kevin R. Thornton ,

* E-mail: krthornt@uci.edu (KRT); tdlong@uci.edu (ADL)

Affiliation Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California, United States of America
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Andrew J. Foran,

Affiliation Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California, United States of America
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Anthony D. Long

* E-mail: krthornt@uci.edu (KRT); tdlong@uci.edu (ADL)

Affiliation Department of Ecology and Evolutionary Biology, University of California Irvine, Irvine, California, United States of America
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Genome-wide association studies
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Mutation
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Heredity
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Deletion mutation
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Simulation and modeling
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Haplotypes
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Medical risk factors
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Alleles
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