A Hybrid Likelihood Model for Sequence-Based Disease Association Studies

Yun-Ching Chen; Hannah Carter; Jennifer Parla; Melissa Kramer; Fernando S. Goes; Mehdi Pirooznia; Peter P. Zandi; W. Richard McCombie; James B. Potash; Rachel Karchin

doi:10.1371/journal.pgen.1003224

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Open Access

Peer-reviewed

Research Article

A Hybrid Likelihood Model for Sequence-Based Disease Association Studies

Yun-Ching Chen,

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Hannah Carter,

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯
Jennifer Parla,

Affiliation Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Melissa Kramer,

Affiliation Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
Fernando S. Goes,

Affiliation Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
Mehdi Pirooznia,

Affiliation Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
Peter P. Zandi,

Affiliation Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
⨯
W. Richard McCombie,

Affiliation Stanley Institute for Cognitive Genomics, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, United States of America
⨯
James B. Potash,

Affiliation Department of Psychiatry, University of Iowa, Iowa City, Iowa, United States of America
⨯
Rachel Karchin

* E-mail: karchin@jhu.edu

Affiliation Department of Biomedical Engineering and Institute for Computational Medicine, Johns Hopkins University, Baltimore, Maryland, United States of America
⨯

A Hybrid Likelihood Model for Sequence-Based Disease Association Studies

Yun-Ching Chen,
Hannah Carter,
Jennifer Parla,
Melissa Kramer,
Fernando S. Goes,
Mehdi Pirooznia,
Peter P. Zandi,
W. Richard McCombie,
James B. Potash,
Rachel Karchin

Published: January 24, 2013
https://doi.org/10.1371/journal.pgen.1003224

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