Coordinated Degradation of Replisome Components Ensures Genome Stability upon Replication Stress in the Absence of the Replication Fork Protection Complex

Open Access

Peer-reviewed

Research Article

Laura C. Roseaulin,

Affiliation Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Chiaki Noguchi,

Affiliation Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Esteban Martinez,

Affiliation Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Melissa A. Ziegler,

Affiliation Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
⨯
Takashi Toda,

Affiliation Laboratory of Cell Regulation, Cancer Research UK, London Research Institute, Lincoln's Inn Field Laboratories, London, United Kingdom
⨯
Eishi Noguchi

* E-mail: enoguchi@drexelmed.edu

Affiliation Department of Biochemistry and Molecular Biology, Drexel University College of Medicine, Philadelphia, Pennsylvania, United States of America
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DNA replication
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Genomics
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Schizosaccharomyces pombe
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Synthesis phase
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Cellular stress responses
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Cell cycle and cell division
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DNA damage
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DNA polymerase
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