Embryos of Robertsonian Translocation Carriers Exhibit a Mitotic Interchromosomal Effect That Enhances Genetic Instability during Early Development

Open Access

Peer-reviewed

Research Article

Samer Alfarawati,

Affiliations Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom, Reprogenetics UK, Institute of Reproductive Sciences, Oxford, United Kingdom
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Elpida Fragouli,

Affiliations Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom, Reprogenetics UK, Institute of Reproductive Sciences, Oxford, United Kingdom
⨯
Pere Colls,

Affiliation Reprogenetics, Livingston, New Jersey, United States of America
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Dagan Wells

* E-mail: dagan.wells@obs-gyn.ox.ac.uk

Affiliations Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, United Kingdom, Reprogenetics UK, Institute of Reproductive Sciences, Oxford, United Kingdom
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Chromosomal translocations
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Embryos
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Aneuploidy
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Chromosome structure and function
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Chromosomes
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Oocytes
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Human genetics
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Miscarriage
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