De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining

Open Access

Peer-reviewed

Research Article

Martin F. Arlt,

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Sountharia Rajendran,

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Shanda R. Birkeland,

Affiliation Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Thomas E. Wilson ,

* E-mail: wilsonte@umich.edu (TEW); glover@umich.edu (TWG)

Affiliations Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Pathology, University of Michigan, Ann Arbor, Michigan, United States of America
⨯
Thomas W. Glover

* E-mail: wilsonte@umich.edu (TEW); glover@umich.edu (TWG)

Affiliation Department of Human Genetics, University of Michigan, Ann Arbor, Michigan, United States of America
⨯

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Non-homologous end joining
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Cloning
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Fibroblasts
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Mammalian genomics
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DNA replication
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DNA repair
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Human genomics
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Polymerase chain reaction
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