Reprogramming to Pluripotency Can Conceal Somatic Cell Chromosomal Instability

Open Access

Peer-reviewed

Research Article

Masakazu Hamada ,

Contributed equally to this work with: Masakazu Hamada, Liviu A. Malureanu

Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America
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Liviu A. Malureanu ,

Contributed equally to this work with: Masakazu Hamada, Liviu A. Malureanu

Affiliations Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
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Tobias Wijshake,

Affiliation Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
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Wei Zhou,

Affiliation Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
⨯
Jan M. van Deursen

* E-mail: vandeursen.jan@mayo.edu

Affiliations Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, United States of America, Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, Minnesota, United States of America
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Cloning
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Induced pluripotent stem cells
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Aneuploidy
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Chromosome structure and function
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Pluripotency
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Karyotypes
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Centromeres
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Teratoma
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