Loss of ATRX, Genome Instability, and an Altered DNA Damage Response Are Hallmarks of the Alternative Lengthening of Telomeres Pathway

• Courtney A. Lovejoy,

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Wendi Li,

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Steven Reisenweber,

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Supawat Thongthip,

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Joanne Bruno,

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Titia de Lange ,

  * E-mail: delange@mail.rockefeller.edu

  Affiliation Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York, United States of America

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• Saurav De,

  Affiliation Molecular Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• John H. J. Petrini,

  Affiliation Molecular Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Patricia A. Sung,

  Affiliation Developmental Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Maria Jasin,

  Affiliation Developmental Biology Program, Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America

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• Joseph Rosenbluh,

  Affiliation Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Yaara Zwang,

  Affiliations Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• Barbara A. Weir,

  Affiliation Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Charlie Hatton,

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• Elena Ivanova,

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• Laura Macconaill,

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• Megan Hanna,

  Affiliation Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• William C. Hahn,

  Affiliations Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America

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• Neal F. Lue,

  Affiliation Department of Microbiology and Immunology, W. R. Hearst Microbiology Research Center, Weill Medical College, Cornell University, New York, New York, United States of America

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• Roger R. Reddel,

  Affiliations Children's Medical Research Institute, Westmead, New South Wales, Australia, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia

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• Yuchen Jiao,

  Affiliation Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, Maryland, United States of America

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• Kenneth Kinzler,

  Affiliation Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, Maryland, United States of America

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• Bert Vogelstein,

  Affiliations Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, Maryland, United States of America, Howard Hughes Medical Institutions, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, Maryland, United States of America

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• Nickolas Papadopoulos,

  Affiliation Ludwig Center for Cancer Genetics and Therapeutics, Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, Maryland, United States of America

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• Alan K. Meeker,

  Affiliation Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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•  [ ... ],
• for the ALT Starr Cancer Consortium
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