Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Irina M. Bochkis; Jonathan Schug; Diana Z. Ye; Svitlana Kurinna; Sabrina A. Stratton; Michelle C. Barton; Klaus H. Kaestner

doi:10.1371/journal.pgen.1002770

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Peer-reviewed

Research Article

Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Irina M. Bochkis,

Current address: Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America

Affiliation Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Jonathan Schug,

Affiliation Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Diana Z. Ye,

Affiliation Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
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Svitlana Kurinna,

Affiliation Center for Stem Cell and Developmental Biology, Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Sabrina A. Stratton,

Affiliation Center for Stem Cell and Developmental Biology, Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Michelle C. Barton,

Affiliation Center for Stem Cell and Developmental Biology, Department of Biochemistry and Molecular Biology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, United States of America
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Klaus H. Kaestner

* E-mail: kaestner@mail.med.upenn.edu

Affiliation Department of Genetics and Institute for Diabetes, Obesity, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
⨯

Genome-Wide Location Analysis Reveals Distinct Transcriptional Circuitry by Paralogous Regulators Foxa1 and Foxa2

Irina M. Bochkis,
Jonathan Schug,
Diana Z. Ye,
Svitlana Kurinna,
Sabrina A. Stratton,
Michelle C. Barton,
Klaus H. Kaestner

Published: June 21, 2012
https://doi.org/10.1371/journal.pgen.1002770

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Forkhead box
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Gene expression
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Sequence motif analysis
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Gene regulation
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Transcription factors
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DNA-binding proteins
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Transcriptional control
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Binding analysis
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