Meta-Analysis of Genome-Wide Scans for Total Body BMD in Children and Adults Reveals Allelic Heterogeneity and Age-Specific Effects at the WNT16 Locus

• Carolina Medina-Gomez ,

  Contributed equally to this work with: Carolina Medina-Gomez, John P. Kemp

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• John P. Kemp ,

  Contributed equally to this work with: Carolina Medina-Gomez, John P. Kemp

  Affiliations MRC CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Karol Estrada,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• Joel Eriksson,

  Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Jeff Liu,

  Affiliation Lexicon Pharmaceuticals, The Woodlands, Texas, United States of America

  ⨯
• Sjur Reppe,

  Affiliation Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway

  ⨯
• David M. Evans,

  Affiliations MRC CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Denise H. M. Heppe,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Liesbeth Vandenput,

  Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Lizbeth Herrera,

  Affiliation Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Susan M. Ring,

  Affiliation Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Claudia J. Kruithof,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• Nicholas J. Timpson,

  Affiliations MRC CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• M. Carola Zillikens,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• Ole K. Olstad,

  Affiliation Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway

  ⨯
• Hou-Feng Zheng,

  Affiliations Department of Medicine, Human Genetics, McGill University, Montreal, Quebec, Canada, Department of Epidemiology and Biostatistics, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada

  ⨯
• J. Brent Richards,

  Affiliations Department of Medicine, Human Genetics, McGill University, Montreal, Quebec, Canada, Department of Epidemiology and Biostatistics, Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada, Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

  ⨯
• Beate St. Pourcain,

  Affiliation MRC CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Albert Hofman,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• Vincent W. V. Jaddoe,

  Affiliations The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Pediatrics, Erasmus University Medical Center, Rotterdam, The Netherlands

  ⨯
• George Davey Smith,

  Affiliations MRC CAiTE Centre, School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom

  ⨯
• Mattias Lorentzon,

  Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Kaare M. Gautvik,

  Affiliations Department of Medical Biochemistry, Oslo University Hospital, Ullevaal, Oslo, Norway, Department of Medical Biochemistry, Oslo Deacon Hospital, Oslo, Norway

  ⨯
• André G. Uitterlinden,

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• Robert Brommage,

  Affiliation Lexicon Pharmaceuticals, The Woodlands, Texas, United States of America

  ⨯
• Claes Ohlsson,

  Affiliation Center for Bone and Arthritis Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

  ⨯
• Jonathan H. Tobias,

  Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom

  ⨯
•  [ ... ],
• Fernando Rivadeneira

  * E-mail: f.rivadeneira@erasmusmc.nl

  Affiliations Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands, The Generation R Study Group, Erasmus University Medical Center, Rotterdam, The Netherlands, Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands, Netherlands Genomics Initiative (NGI)–sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam, The Netherlands

  ⨯
• [ view all ]
• [ view less ]