Negative Supercoiling Creates Single-Stranded Patches of DNA That Are Substrates for AID–Mediated Mutagenesis

Open Access

Peer-reviewed

Research Article

Jahan-Yar Parsa,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Shaliny Ramachandran,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Ahmad Zaheen,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Rajeev M. Nepal,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Anat Kapelnikov,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Antoaneta Belcheva,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Maribel Berru,

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯
Diana Ronai,

Affiliation Howard Hughes Medical Institute, Department of Molecular, Cellular, and Developmental Biology, University of Colorado at Boulder, Boulder, Colorado, United States of America
⨯
Alberto Martin

* E-mail: alberto.martin@utoronto.ca

Affiliation Department of Immunology, University of Toronto, Toronto, Canada
⨯

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B cells
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DNA transcription
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Cloning
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Mutation
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RNA polymerase
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Nucleotides
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DNA
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RNA hybridization
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