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Open Access
Peer-reviewed
Research Article
Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes
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Josine L. Min ,
* E-mail: jlmin@well.ox.ac.uk (JLM); krinaz@well.ox.ac.uk (KTZ)
Affiliation The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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George Nicholson,
Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom
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Ingileif Halgrimsdottir,
Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom
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Kristian Almstrup,
Affiliation Department of Molecular Genetics, Novo Nordisk A/S, Maaloev, Denmark
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Andreas Petri,
Affiliation Department of Molecular Genetics, Novo Nordisk A/S, Maaloev, Denmark
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Amy Barrett,
Affiliation Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom
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Mary Travers,
Affiliation Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom
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Nigel W. Rayner,
Affiliations The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom
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Reedik Mägi,
Affiliations The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Estonian Genome Center, University of Tartu, Tartu, Estonia
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Fredrik H. Pettersson,
Affiliation The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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John Broxholme,
Affiliation The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Matt J. Neville,
Affiliations Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, ORH Trust, Churchill Hospital, Oxford, United Kingdom
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Quin F. Wills,
Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom
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Jane Cheeseman,
Affiliation Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom
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The GIANT Consortium ,
¶Memberships of the consortia are listed in Text S1.
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The MolPAGE Consortium ,
¶Memberships of the consortia are listed in Text S1.
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Maxine Allen,
Affiliation Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom
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Chris C. Holmes,
Affiliations The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Department of Statistics, University of Oxford, Oxford, United Kingdom
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Tim D. Spector,
Affiliation Twin Research Unit, King's College London, London, United Kingdom
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Jan Fleckner,
Affiliation Department of Molecular Genetics, Novo Nordisk A/S, Maaloev, Denmark
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Mark I. McCarthy,
Affiliations The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, ORH Trust, Churchill Hospital, Oxford, United Kingdom
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Fredrik Karpe,
Affiliations Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford, United Kingdom, NIHR Oxford Biomedical Research Centre, ORH Trust, Churchill Hospital, Oxford, United Kingdom
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Cecilia M. Lindgren,
Affiliation The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Krina T. Zondervan
* E-mail: jlmin@well.ox.ac.uk (JLM); krinaz@well.ox.ac.uk (KTZ)
Affiliation The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes
- Josine L. Min,
- George Nicholson,
- Ingileif Halgrimsdottir,
- Kristian Almstrup,
- Andreas Petri,
- Amy Barrett,
- Mary Travers,
- Nigel W. Rayner,
- Reedik Mägi,
- Fredrik H. Pettersson
- Published: February 23, 2012
- https://doi.org/10.1371/journal.pgen.1002505