Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals

• Yingleong Chan ,

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America, Children's Hospital Boston, Boston, Massachusetts, United States of America

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• Oddgeir L. Holmen ,

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  Affiliations HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway, St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway

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• Andrew Dauber ,

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  Affiliations Broad Institute, Cambridge, Massachusetts, United States of America, Children's Hospital Boston, Boston, Massachusetts, United States of America

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• Lars Vatten,

  Affiliation Department of Public Health and General Practice, Norwegian University of Science and Technology, Trondheim, Norway

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• Aki S. Havulinna,

  Affiliation National Institute for Health and Welfare, Helsinki, Finland

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• Frank Skorpen,

  Affiliation Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Trondheim, Norway

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• Kirsti Kvaløy,

  Affiliation HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway

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• Kaisa Silander,

  Affiliations National Institute for Health and Welfare, Helsinki, Finland, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland

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• Thutrang T. Nguyen,

  Affiliation Children's Hospital Boston, Boston, Massachusetts, United States of America

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• Cristen Willer,

  Affiliation Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Michael Boehnke,

  Affiliation Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, Michigan, United States of America

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• Markus Perola,

  Affiliations National Institute for Health and Welfare, Helsinki, Finland, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Estonian Genome Project, University of Tartu, Tartu, Estonia

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• Aarno Palotie,

  Affiliations Broad Institute, Cambridge, Massachusetts, United States of America, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Medical Genetics, University of Helsinki and University Central Hospital, Helsinki, Finland

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• Veikko Salomaa,

  Affiliation National Institute for Health and Welfare, Helsinki, Finland

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• Kristian Hveem,

  Affiliation HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway

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• Timothy M. Frayling ,

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  Affiliation Genetics of Complex Traits, Peninsula Medical School, University of Exeter, Exeter, United Kingdom

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• Joel N. Hirschhorn ,

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  * E-mail: joelh@broadinstitute.org(JNH); michael.weedon@pms.ac.uk (MNW)

  Affiliations Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute, Cambridge, Massachusetts, United States of America, Children's Hospital Boston, Boston, Massachusetts, United States of America

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•  [ ... ],
• Michael N. Weedon

  Contributed equally to this work with: Yingleong Chan, Oddgeir L. Holmen, Andrew Dauber, Timothy M. Frayling, Joel N. Hirschhorn, Michael N. Weedon

  * E-mail: joelh@broadinstitute.org(JNH); michael.weedon@pms.ac.uk (MNW)

  Affiliation Genetics of Complex Traits, Peninsula Medical School, University of Exeter, Exeter, United Kingdom

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