Positive Selection for New Disease Mutations in the Human Germline: Evidence from the Heritable Cancer Syndrome Multiple Endocrine Neoplasia Type 2B

• Soo-Kyung Choi ,

  Contributed equally to this work with: Soo-Kyung Choi, Song-Ro Yoon

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, California, United States of America

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• Song-Ro Yoon ,

  Contributed equally to this work with: Soo-Kyung Choi, Song-Ro Yoon

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, California, United States of America

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• Peter Calabrese ,

  * E-mail: petercal@usc.edu (PC); arnheim@usc.edu (NA)

  ¶These authors also contributed equally to this work.

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, California, United States of America

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• Norman Arnheim

  * E-mail: petercal@usc.edu (PC); arnheim@usc.edu (NA)

  ¶These authors also contributed equally to this work.

  Affiliation Molecular and Computational Biology Program, University of Southern California, Los Angeles, California, United States of America

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