A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

Paula S. Ramos; Lindsey A. Criswell; Kathy L. Moser; Mary E. Comeau; Adrienne H. Williams; Nicholas M. Pajewski; Sharon A. Chung; Robert R. Graham; Raphael Zidovetzki; Jennifer A. Kelly; Kenneth M. Kaufman; Chaim O. Jacob; Timothy J. Vyse; Betty P. Tsao; Robert P. Kimberly; Patrick M. Gaffney; Marta E. Alarcón-Riquelme; John B. Harley; Carl D. Langefeld; for The International Consortium on the Genetics of Systemic Erythematosus (SLEGEN)

doi:10.1371/journal.pgen.1002406

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Open Access

Peer-reviewed

Research Article

A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

Paula S. Ramos ,

* E-mail: ramosp@musc.edu

Affiliation Department of Medicine, Medical University of South Carolina, Charleston, South Carolina, United States of America
⨯
Lindsey A. Criswell,

Affiliation Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, San Francisco, California, United States of America
⨯
Kathy L. Moser,

Affiliation Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Mary E. Comeau,

Affiliation Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America
⨯
Adrienne H. Williams,

Affiliation Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America
⨯
Nicholas M. Pajewski,

Affiliation Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America
⨯
Sharon A. Chung,

Affiliation Rosalind Russell Medical Research Center for Arthritis, University of California San Francisco, San Francisco, California, United States of America
⨯
Robert R. Graham,

Affiliation Immunology Biomarkers Group, Genentech, South San Francisco, California, United States of America
⨯
Raphael Zidovetzki,

Affiliation Department of Cell Biology and Neuroscience, University of California Riverside, Riverside, California, United States of America
⨯
Jennifer A. Kelly,

Affiliation Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Kenneth M. Kaufman,

Affiliation Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
⨯
Chaim O. Jacob,

Affiliation Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, United States of America
⨯
Timothy J. Vyse,

Affiliation Division of Genetics and Molecular Medicine, King's College London, London, United Kingdom
⨯
Betty P. Tsao,

Affiliation David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
⨯
Robert P. Kimberly,

Affiliation Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
⨯
Patrick M. Gaffney,

Affiliation Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America
⨯
Marta E. Alarcón-Riquelme,

Affiliations Arthritis and Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America, Centro de Genómica y Investigaciones Oncológicas, Pfizer-Universidad de Granada-Junta de Andalucía, Granada, Spain
⨯
John B. Harley,

Affiliation Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
⨯
Carl D. Langefeld,

Affiliation Department of Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, North Carolina, United States of America
⨯
[ ... ],
for The International Consortium on the Genetics of Systemic Erythematosus (SLEGEN)

¶Membership of SLEGEN is provided in the Acknowledgments.
⨯
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A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap

Paula S. Ramos,
Lindsey A. Criswell,
Kathy L. Moser,
Mary E. Comeau,
Adrienne H. Williams,
Nicholas M. Pajewski,
Sharon A. Chung,
Robert R. Graham,
Raphael Zidovetzki,
Jennifer A. Kelly

Published: December 8, 2011
https://doi.org/10.1371/journal.pgen.1002406

Reader Comments (2)

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21 Jun 2012
17:24 GMT
Most Recent

Happy for study. Posted by btufts on 21 Jun 2012 at 17:24 GMT
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13 Dec 2011
20:41 GMT
Most Recent

Very interesting addition Posted by agonzalez1 on 13 Dec 2011 at 20:41 GMT

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