The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Sylvia E. J. Fischer; Taiowa A. Montgomery; Chi Zhang; Noah Fahlgren; Peter C. Breen; Alexia Hwang; Christopher M. Sullivan; James C. Carrington; Gary Ruvkun

doi:10.1371/journal.pgen.1002369

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Peer-reviewed

Research Article

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Sylvia E. J. Fischer,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Taiowa A. Montgomery,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Chi Zhang,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Noah Fahlgren,

Affiliation Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America
⨯
Peter C. Breen,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Alexia Hwang,

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Christopher M. Sullivan,

Affiliation Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America
⨯
James C. Carrington,

Affiliation Center for Genome Research and Biocomputing, Oregon State University, Corvallis, Oregon, United States of America
⨯
Gary Ruvkun

* E-mail: ruvkun@molbio.mgh.harvard.edu

Affiliation Department of Molecular Biology, Massachusetts General Hospital, Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
⨯

The ERI-6/7 Helicase Acts at the First Stage of an siRNA Amplification Pathway That Targets Recent Gene Duplications

Sylvia E. J. Fischer,
Taiowa A. Montgomery,
Chi Zhang,
Noah Fahlgren,
Peter C. Breen,
Alexia Hwang,
Christopher M. Sullivan,
James C. Carrington,
Gary Ruvkun

Published: November 10, 2011
https://doi.org/10.1371/journal.pgen.1002369

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