A Systems Biology Approach Reveals the Role of a Novel Methyltransferase in Response to Chemical Stress and Lipid Homeostasis

• Elena Lissina,

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada

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• Brian Young,

  Affiliation Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Malene L. Urbanus,

  Affiliations Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

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• Xue Li Guan,

  Affiliations Department of Biological Sciences, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore, Department of Biochemistry, University of Geneva, Geneva, Switzerland

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• Jonathan Lowenson,

  Affiliation Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Shawn Hoon,

  Affiliation Molecular Engineering Lab, Agency for Science, Technology, and Research, Singapore, Singapore

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• Anastasia Baryshnikova,

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada

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• Isabelle Riezman,

  Affiliation Department of Biochemistry, University of Geneva, Geneva, Switzerland

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• Magali Michaut,

  Affiliation Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada

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• Howard Riezman,

  Affiliation Department of Biochemistry, University of Geneva, Geneva, Switzerland

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• Leah E. Cowen,

  Affiliation Department of Molecular Genetics, University of Toronto, Toronto, Canada

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• Markus R. Wenk,

  Affiliation Department of Biological Sciences, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

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• Steven G. Clarke,

  Affiliation Department of Chemistry and Biochemistry and the Molecular Biology Institute, University of California Los Angeles, Los Angeles, California, United States of America

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• Guri Giaever,

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada, Department of Pharmacy and Pharmaceutical Sciences, University of Toronto, Toronto, Canada

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• Corey Nislow

  * E-mail: corey.nislow@utoronto.ca

  Affiliations Department of Molecular Genetics, University of Toronto, Toronto, Canada, Terrence Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Canada, Banting and Best Department of Medical Research, University of Toronto, Toronto, Canada

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