A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice

Kiyoto Kurima; Ronna Hertzano; Oksana Gavrilova; Kelly Monahan; Karl B. Shpargel; Garani Nadaraja; Yoshiyuki Kawashima; Kyu Yup Lee; Taku Ito; Yujiro Higashi; David J. Eisenman; Scott E. Strome; Andrew J. Griffith

doi:10.1371/journal.pgen.1002307

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Peer-reviewed

Research Article

A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice

Kiyoto Kurima,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Ronna Hertzano,

Affiliation Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America
⨯
Oksana Gavrilova,

Affiliation Mouse Metabolism Core Laboratory, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Kelly Monahan,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Karl B. Shpargel,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Garani Nadaraja,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Yoshiyuki Kawashima,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Kyu Yup Lee,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Taku Ito,

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯
Yujiro Higashi,

Affiliation Department of Perinatology, Institute for Developmental Research, Aichi Human Service Center, Kasugai, Japan
⨯
David J. Eisenman,

Affiliation Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America
⨯
Scott E. Strome,

Affiliation Department of Otorhinolaryngology–Head and Neck Surgery, University of Maryland, Baltimore, Maryland, United States of America
⨯
Andrew J. Griffith

* E-mail: griffita@nidcd.nih.gov

Affiliation Otolaryngology Branch, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Rockville, Maryland, United States of America
⨯

A Noncoding Point Mutation of Zeb1 Causes Multiple Developmental Malformations and Obesity in Twirler Mice

Kiyoto Kurima,
Ronna Hertzano,
Oksana Gavrilova,
Kelly Monahan,
Karl B. Shpargel,
Garani Nadaraja,
Yoshiyuki Kawashima,
Kyu Yup Lee,
Taku Ito,
Yujiro Higashi

Published: September 29, 2011
https://doi.org/10.1371/journal.pgen.1002307

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