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Open Access
Peer-reviewed
Research Article
Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis
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Vardhman K. Rakyan ,
Contributed equally to this work with: Vardhman K. Rakyan, Huriya Beyan, Thomas A. Down
* E-mail: v.rakyan@qmul.ac.uk (VKR); r.d.g.leslie@qmul.ac.uk (RDL)
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Huriya Beyan ,
Contributed equally to this work with: Vardhman K. Rakyan, Huriya Beyan, Thomas A. Down
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Thomas A. Down ,
Contributed equally to this work with: Vardhman K. Rakyan, Huriya Beyan, Thomas A. Down
Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom
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Mohammed I. Hawa,
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Siarhei Maslau,
Affiliation The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom
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Deeqo Aden,
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Antoine Daunay,
Affiliation Laboratory for Functional Genomics, Fondation Jean-Dausset – CEPH, Paris, France
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Florence Busato,
Affiliation Laboratory for Epigenetics, Centre National de Génotypage, CEA – Institut de Génomique, Evry, France
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Charles A. Mein,
Affiliation The Genome Centre, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, The Sir John Vane Science Centre, London, United Kingdom
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Burkhard Manfras,
Affiliation Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Medical Center Ulm and Center of Excellence “Metabolic Disorders” Baden-Württemberg, Ulm, Germany
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Kerith-Rae M. Dias,
Affiliation The Genome Centre, Queen Mary University of London, Barts and The London School of Medicine and Dentistry, The Sir John Vane Science Centre, London, United Kingdom
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Christopher G. Bell,
Affiliation UCL Cancer Institute, University College London, London, United Kingdom
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Jörg Tost,
Affiliations Laboratory for Functional Genomics, Fondation Jean-Dausset – CEPH, Paris, France, Laboratory for Epigenetics, Centre National de Génotypage, CEA – Institut de Génomique, Evry, France
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Bernhard O. Boehm,
Affiliation Division of Endocrinology and Diabetes, Department of Internal Medicine I, University Medical Center Ulm and Center of Excellence “Metabolic Disorders” Baden-Württemberg, Ulm, Germany
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Stephan Beck,
Affiliation UCL Cancer Institute, University College London, London, United Kingdom
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R. David Leslie
* E-mail: v.rakyan@qmul.ac.uk (VKR); r.d.g.leslie@qmul.ac.uk (RDL)
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
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Identification of Type 1 Diabetes–Associated DNA Methylation Variable Positions That Precede Disease Diagnosis
- Vardhman K. Rakyan,
- Huriya Beyan,
- Thomas A. Down,
- Mohammed I. Hawa,
- Siarhei Maslau,
- Deeqo Aden,
- Antoine Daunay,
- Florence Busato,
- Charles A. Mein,
- Burkhard Manfras
- Published: September 29, 2011
- https://doi.org/10.1371/journal.pgen.1002300