Pervasive Sharing of Genetic Effects in Autoimmune Disease

• Chris Cotsapas ,

  Contributed equally to this work with: Chris Cotsapas, Benjamin F. Voight

  Affiliations Center For Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, United States of America, Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Benjamin F. Voight ,

  Contributed equally to this work with: Chris Cotsapas, Benjamin F. Voight

  Affiliations Center For Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America

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• Elizabeth Rossin,

  Affiliations Center For Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Health Science and Technology MD Program, Harvard University and Massachusetts Institute of Technology, Boston, Massachusetts, United States of America, Harvard Biological and Biomedical Sciences Program, Harvard University, Boston, Massachusetts, United States of America

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• Kasper Lage,

  Affiliations Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Pediatric Surgical Research Laboratories, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Lyngby, Denmark

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• Benjamin M. Neale,

  Affiliations Center For Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Analytical and Translational Genetics Unity, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Chris Wallace,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• Gonçalo R. Abecasis,

  Affiliation Center for Statistical Genetics, University of Michigan, Ann Arbor, Massachusetts, United States of America

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• Jeffrey C. Barrett,

  Affiliation Human Genetics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom

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• Timothy Behrens,

  Affiliation Genentech, South San Francisco, California, United States of America

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• Judy Cho,

  Affiliations Department of Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America, Departments of Medicine and Genetics, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Philip L. De Jager,

  Affiliations Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• James T. Elder,

  Affiliation Department of Dermatology, University of Michigan, Ann Arbor, Michigan, United States of America

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• Robert R. Graham,

  Affiliation Genentech, South San Francisco, California, United States of America

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• Peter Gregersen,

  Affiliation Feinstein Institute for Medical Research, North Shore-Long Island Jewish Health System, Manhasset, New York, United States of America

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• Lars Klareskog,

  Affiliation Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

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• Katherine A. Siminovitch,

  Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada

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• David A. van Heel,

  Affiliation Blizard Institute, The London School of Medicine and Dentistry, London, United Kingdom

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• Cisca Wijmenga,

  Affiliation Department of Genetics, University Medical Center Groningen and Groningen University, Groningen, The Netherlands

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• Jane Worthington,

  Affiliation Arthritis Research UK Epidemiology Unit, School of Translational Medicine, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, United Kingdom

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• John A. Todd,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• David A. Hafler,

  Affiliation Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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• Stephen S. Rich,

  Affiliation Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, United States of America

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• Mark J. Daly ,

  * E-mail: mjdaly@atgu.mgh.harvard.edu

  Affiliations Center For Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America, Analytical and Translational Genetics Unity, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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