Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

• Minh T. N. Le ,

  Contributed equally to this work with: Minh T. N. Le, Ng Shyh-Chang

  Affiliations Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore, Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America, Computation and Systems Biology, Singapore–MIT Alliance, Singapore, Singapore

  ⨯
• Ng Shyh-Chang ,

  Contributed equally to this work with: Minh T. N. Le, Ng Shyh-Chang

  Affiliations Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Swea Ling Khaw,

  Affiliations Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore, NUS Graduate School for Integrative Sciences and Engineering, Singapore, Singapore

  ⨯
• Lingzi Chin,

  Affiliation Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore

  ⨯
• Cathleen Teh,

  Affiliation Fish Developmental Biology, Institute of Molecular and Cell Biology, Singapore, Singapore

  ⨯
• Junliang Tay,

  Affiliation Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore

  ⨯
• Elizabeth O'Day,

  Affiliation Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Vladimir Korzh,

  Affiliation NUS Graduate School for Integrative Sciences and Engineering, Singapore, Singapore

  ⨯
• Henry Yang,

  Affiliation Bioinformatics Group, Singapore Immunology Network, Singapore, Singapore

  ⨯
• Ashish Lal,

  Affiliations Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America, Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Judy Lieberman,

  Affiliation Immune Disease Institute and Program in Cellular and Molecular Medicine, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯
• Harvey F. Lodish ,

  * E-mail: limb1@gis.a-star.edu.sg, blim@bidmc.havard.edu (BL); lodish@wi.mit.edu (HFL)

  Affiliations Computation and Systems Biology, Singapore–MIT Alliance, Singapore, Singapore, Whitehead Institute for Biomedical Research, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Bing Lim

  * E-mail: limb1@gis.a-star.edu.sg, blim@bidmc.havard.edu (BL); lodish@wi.mit.edu (HFL)

  Affiliations Stem Cell and Developmental Biology, Genome Institute of Singapore, Singapore, Singapore, Computation and Systems Biology, Singapore–MIT Alliance, Singapore, Singapore, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯