Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

Vincent Plagnol; Joanna M. M. Howson; Deborah J. Smyth; Neil Walker; Jason P. Hafler; Chris Wallace; Helen Stevens; Laura Jackson; Matthew J. Simmonds; Type 1 Diabetes Genetics Consortium; Polly J. Bingley; Stephen C. Gough; John A. Todd

doi:10.1371/journal.pgen.1002216

Loading metrics

Open Access

Peer-reviewed

Research Article

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

Vincent Plagnol ,

* E-mail: v.plagnol@ucl.ac.uk (VP); john.todd@cimr.cam.ac.uk (JAT)

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Joanna M. M. Howson,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Deborah J. Smyth,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Neil Walker,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Jason P. Hafler,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Chris Wallace,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Helen Stevens,

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯
Laura Jackson,

Affiliation University Hospitals Birmingham, Birmingham, United Kingdom
⨯
Matthew J. Simmonds,

Affiliation The Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Headington, Oxford, United Kingdom
⨯
Type 1 Diabetes Genetics Consortium,
Polly J. Bingley,

Affiliation School of Clinical Sciences, University of Bristol, Bristol, United Kingdom
⨯
Stephen C. Gough,

Affiliation The Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Headington, Oxford, United Kingdom
⨯
John A. Todd

* E-mail: v.plagnol@ucl.ac.uk (VP); john.todd@cimr.cam.ac.uk (JAT)

Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Department of Medical Genetics, Cambridge Institute for Medical Research, National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge, United Kingdom
⨯

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

Vincent Plagnol,
Joanna M. M. Howson,
Deborah J. Smyth,
Neil Walker,
Jason P. Hafler,
Chris Wallace,
Helen Stevens,
Laura Jackson,
Matthew J. Simmonds,
Type 1 Diabetes Genetics Consortium

Published: August 4, 2011
https://doi.org/10.1371/journal.pgen.1002216

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Autoantibodies
Is the Subject Area "Autoantibodies" applicable to this article?

Thanks for your feedback.
Graves' disease
Is the Subject Area "Graves' disease" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Genetic loci
Is the Subject Area "Genetic loci" applicable to this article?

Thanks for your feedback.
Principal component analysis
Is the Subject Area "Principal component analysis" applicable to this article?

Thanks for your feedback.
Diabetes mellitus
Is the Subject Area "Diabetes mellitus" applicable to this article?

Thanks for your feedback.
Medical risk factors
Is the Subject Area "Medical risk factors" applicable to this article?

Thanks for your feedback.
Genome-wide association studies
Is the Subject Area "Genome-wide association studies" applicable to this article?

Thanks for your feedback.