-
Loading metrics
Open Access
Peer-reviewed
Research Article
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
-
Rudolf S. N. Fehrmann,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Ritsert C. Jansen ,
Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra
Affiliation Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
⨯ -
Jan H. Veldink ,
Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra
Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯ -
Harm-Jan Westra ,
Contributed equally to this work with: Ritsert C. Jansen, Jan H. Veldink, Harm-Jan Westra
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Danny Arends,
Affiliation Groningen Bioinformatics Centre, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Haren, The Netherlands
⨯ -
Marc Jan Bonder,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Jingyuan Fu,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Patrick Deelen,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Harry J. M. Groen,
Affiliation Department of Pulmonology, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Asia Smolonska,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Rinse K. Weersma,
Affiliations Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands, Department of Gastroenterology and Hepatology, University Medical Centre Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Robert M. W. Hofstra,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Wim A. Buurman,
Affiliation NUTRIM School for Nutrition, Toxicology, and Metabolism, Department of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands
⨯ -
Sander Rensen,
Affiliation NUTRIM School for Nutrition, Toxicology, and Metabolism, Department of General Surgery, Maastricht University Medical Center, Maastricht, The Netherlands
⨯ -
Marcel G. M. Wolfs,
Affiliation Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Mathieu Platteel,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Alexandra Zhernakova,
Affiliation Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands
⨯ -
Clara C. Elbers,
Affiliation Department of Genetics, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯ -
Eleanora M. Festen,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Gosia Trynka,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Marten H. Hofker,
Affiliation Department of Pathology and Medical Biology, Medical Biology Section, Molecular Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Christiaan G. J. Saris,
Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯ -
Roel A. Ophoff,
Affiliations Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands, Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands, Center for Neurobehavioral Genetics, University of California Los Angeles, Los Angeles, California, United States of America
⨯ -
Leonard H. van den Berg,
Affiliation Department of Neurology, Rudolf Magnus Institute of Neuroscience, University Medical Centre Utrecht, Utrecht, The Netherlands
⨯ -
David A. van Heel,
Affiliation Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
⨯ -
Cisca Wijmenga,
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ -
Gerard J. te Meerman ,
¶These authors also contributed equally to this work.
Affiliation Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands
⨯ - [ ... ],
-
Lude Franke
* E-mail: lude@ludesign.nl
¶These authors also contributed equally to this work.
Affiliations Department of Genetics, University Medical Center Groningen and University of Groningen, Groningen, The Netherlands, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, United Kingdom
⨯ - [ view all ]
- [ view less ]
Trans-eQTLs Reveal That Independent Genetic Variants Associated with a Complex Phenotype Converge on Intermediate Genes, with a Major Role for the HLA
- Rudolf S. N. Fehrmann,
- Ritsert C. Jansen,
- Jan H. Veldink,
- Harm-Jan Westra,
- Danny Arends,
- Marc Jan Bonder,
- Jingyuan Fu,
- Patrick Deelen,
- Harry J. M. Groen,
- Asia Smolonska
- Published: August 4, 2011
- https://doi.org/10.1371/journal.pgen.1002197