A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus

• Xiaobing Luo ,

  Contributed equally to this work with: Xiaobing Luo, Wanling Yang

  Affiliations Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China, Key Laboratory of Stem Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Wanling Yang ,

  Contributed equally to this work with: Xiaobing Luo, Wanling Yang

  Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China

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• Dong-Qing Ye,

  Affiliation Department of Epidemiology and Biostatistics, Anhui Medical University School of Public Health, Hefei, Anhui, China

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• Huijuan Cui,

  Affiliations Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China, Key Laboratory of Stem Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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• Yan Zhang,

  Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China

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• Nattiya Hirankarn,

  Affiliation Lupus Research Unit, Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

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• Xiaoxia Qian,

  Affiliation Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China

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• Yuanjia Tang,

  Affiliation Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China

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• Yu Lung Lau,

  Affiliation Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, University of Hong Kong, Hong Kong, China

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• Niek de Vries,

  Affiliation Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Paul Peter Tak,

  Affiliation Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

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• Betty P. Tsao,

  Affiliation Division of Rheumatology, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America

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• Nan Shen

  * E-mail: nanshensibs@gmail.com

  Affiliation Joint Molecular Rheumatology Laboratory of the Institute of Health Sciences and Shanghai Renji Hospital, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China

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