Alkylation Base Damage Is Converted into Repairable Double-Strand Breaks and Complex Intermediates in G2 Cells Lacking AP Endonuclease

Open Access

Peer-reviewed

Research Article

Wenjian Ma,

Affiliation Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Jim W. Westmoreland,

Affiliation Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, Research Triangle Park, North Carolina, United States of America
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Dmitry A. Gordenin,

Affiliation Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, Research Triangle Park, North Carolina, United States of America
⨯
Mike A. Resnick

* E-mail: resnick@niehs.nih.gov

Affiliation Chromosome Stability Group, Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, Research Triangle Park, North Carolina, United States of America
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DNA repair
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Yeast
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Ethidium bromide staining
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Southern blot
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Chromosomal DNA
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Recombinational repair
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Chromatids
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DNA recombination
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