Does Positive Selection Drive Transcription Factor Binding Site Turnover? A Test with Drosophila Cis-Regulatory Modules

Open Access

Peer-reviewed

Research Article

Bin Z. He ,

* E-mail: hebin@uchicago.edu

Affiliation Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America
⨯
Alisha K. Holloway,

Affiliation Gladstone Institute, University of California San Francisco, San Francisco, California, United States of America
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Sebastian J. Maerkl,

Affiliation Laboratory of Biological Network Characterization (LBNC), École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland
⨯
Martin Kreitman

Affiliations Department of Ecology and Evolution, The University of Chicago, Chicago, Illinois, United States of America, Committee on Genetics, Genomics, and Systems Biology, The University of Chicago, Chicago, Illinois, United States of America
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Genetic footprinting
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Drosophila melanogaster
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Substitution mutation
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Evolutionary genetics
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Mutation detection
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Deletion mutation
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Invertebrate genomics
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Sequence alignment
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