AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants

Open Access

Peer-reviewed

Research Article

José F. Ruiz,

Affiliation Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla–CSIC, Sevilla, Spain
⨯
Belén Gómez-González,

Affiliation Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla–CSIC, Sevilla, Spain
⨯
Andrés Aguilera

* E-mail: aguilo@us.es

Affiliation Centro Andaluz de Biología Molecular y Medicina Regenerativa (CABIMER), Universidad de Sevilla–CSIC, Sevilla, Spain
⨯

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Yeast
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Chromosomal translocations
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B cells
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DNA transcription
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Introns
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DNA repair
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Biosynthesis
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DNA recombination
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