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Open Access
Peer-reviewed
Research Article
The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study
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Alexandra C. Nica,
Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
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Leopold Parts,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Daniel Glass,
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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James Nisbet,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Amy Barrett,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Magdalena Sekowska,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Mary Travers,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Simon Potter,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Elin Grundberg,
Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom
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Kerrin Small,
Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom
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Åsa K. Hedman,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Veronique Bataille,
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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Jordana Tzenova Bell,
Affiliations Department of Twin Research, King's College London, London, United Kingdom, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Gabriela Surdulescu,
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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Antigone S. Dimas,
Affiliations Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Catherine Ingle,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Frank O. Nestle,
Affiliation St. John's Institute of Dermatology, King's College London, London, United Kingdom
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Paola di Meglio,
Affiliation St. John's Institute of Dermatology, King's College London, London, United Kingdom
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Josine L. Min,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Alicja Wilk,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Christopher J. Hammond,
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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Neelam Hassanali,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Tsun-Po Yang,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Stephen B. Montgomery,
Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
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Steve O'Rahilly,
Affiliation University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom
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Cecilia M. Lindgren,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Krina T. Zondervan,
Affiliation Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Nicole Soranzo,
Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, Department of Twin Research, King's College London, London, United Kingdom
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Inês Barroso,
Affiliations Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom, University of Cambridge Metabolic Research Labs, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, United Kingdom
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Richard Durbin,
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Kourosh Ahmadi,
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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Panos Deloukas ,
* E-mail: emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)
Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, United Kingdom
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Mark I. McCarthy ,
* E-mail: emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)
Affiliations Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom, Oxford Centre for Diabetes, Endocrinology, and Metabolism, University of Oxford, Churchill Hospital, Oxford, United Kingdom, Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford, United Kingdom
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Emmanouil T. Dermitzakis ,
* E-mail: emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)
Affiliation Department of Genetic Medicine and Development, University of Geneva Medical School, Geneva, Switzerland
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Timothy D. Spector ,
* E-mail: emmanouil.dermitzakis@unige.ch (ETD); tim.spector@kcl.ac.uk (TDS); mark.mccarthy@drl.ox.ac.uk (MIM); panos@sanger.ac.uk (PD)
Affiliation Department of Twin Research, King's College London, London, United Kingdom
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- The MuTHER Consortium
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The Architecture of Gene Regulatory Variation across Multiple Human Tissues: The MuTHER Study
- Alexandra C. Nica,
- Leopold Parts,
- Daniel Glass,
- James Nisbet,
- Amy Barrett,
- Magdalena Sekowska,
- Mary Travers,
- Simon Potter,
- Elin Grundberg,
- Kerrin Small
- Published: February 3, 2011
- https://doi.org/10.1371/journal.pgen.1002003