Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome

Toshiyuki Bohgaki; Miyuki Bohgaki; Renato Cardoso; Stephanie Panier; Dimphy Zeegers; Li Li; Grant S. Stewart; Otto Sanchez; M. Prakash Hande; Daniel Durocher; Anne Hakem; Razqallah Hakem

doi:10.1371/journal.pgen.1001381

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Open Access

Peer-reviewed

Research Article

Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome

Toshiyuki Bohgaki ,

Contributed equally to this work with: Toshiyuki Bohgaki, Miyuki Bohgaki

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯
Miyuki Bohgaki ,

Contributed equally to this work with: Toshiyuki Bohgaki, Miyuki Bohgaki

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯
Renato Cardoso,

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯
Stephanie Panier,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
⨯
Dimphy Zeegers,

Affiliation Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore
⨯
Li Li,

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯
Grant S. Stewart,

Affiliation Cancer Research UK, Institute for Cancer Studies, Birmingham University, Birmingham, United Kingdom
⨯
Otto Sanchez,

Affiliation University of Ontario Institute of Technology, Oshawa, Canada
⨯
M. Prakash Hande,

Affiliation Cancer Research UK, Institute for Cancer Studies, Birmingham University, Birmingham, United Kingdom
⨯
Daniel Durocher,

Affiliation Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
⨯
Anne Hakem ,

* E-mail: ahakem@uhnres.utoronto.ca (AH); rhakem@uhnres.utoronto.ca (RH)

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯
Razqallah Hakem

* E-mail: ahakem@uhnres.utoronto.ca (AH); rhakem@uhnres.utoronto.ca (RH)

Affiliation Ontario Cancer Institute, University Health Network and Department of Medical Biophysics, University of Toronto, Toronto, Canada
⨯

Genomic Instability, Defective Spermatogenesis, Immunodeficiency, and Cancer in a Mouse Model of the RIDDLE Syndrome

Toshiyuki Bohgaki,
Miyuki Bohgaki,
Renato Cardoso,
Stephanie Panier,
Dimphy Zeegers,
Li Li,
Grant S. Stewart,
Otto Sanchez,
M. Prakash Hande,
Daniel Durocher

Published: April 28, 2011
https://doi.org/10.1371/journal.pgen.1001381

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