SUMO-Targeted Ubiquitin Ligase, Rad60, and Nse2 SUMO Ligase Suppress Spontaneous Top1–Mediated DNA Damage and Genome Instability

Open Access

Peer-reviewed

Research Article

Johanna Heideker,

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
⨯
John Prudden,

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
⨯
J. Jefferson P. Perry,

Affiliations Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, School of Biotechnology, Amrita Vishwa Vidya Peetham, Amritapuri, Kerala, India
⨯
John A. Tainer,

Affiliations Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America, Life Sciences Division, Department of Molecular Biology, Lawrence Berkeley National Laboratory, Berkeley, California, United States of America
⨯
Michael N. Boddy

* E-mail: nboddy@scripps.edu

Affiliation Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America
⨯

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DNA repair
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Schizosaccharomyces pombe
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SUMOylation
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DNA damage
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Ligases
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DNA replication
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Genomics
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Saccharomyces cerevisiae
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