CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Dong-Hoon Lee; Purnima Singh; Shirley Y. Tsai; Nathan Oates; Alexander Spalla; Claudio Spalla; Lucy Brown; Guillermo Rivas; Garrett Larson; Tibor A. Rauch; Gerd P. Pfeifer; Piroska E. Szabó

doi:10.1371/journal.pgen.1001224

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Peer-reviewed

Research Article

CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Dong-Hoon Lee ,

Contributed equally to this work with: Dong-Hoon Lee, Purnima Singh

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Purnima Singh ,

Contributed equally to this work with: Dong-Hoon Lee, Purnima Singh

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Shirley Y. Tsai,

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Nathan Oates,

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Alexander Spalla,

Affiliation Shared Recourses, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Claudio Spalla,

Affiliation Shared Recourses, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Lucy Brown,

Affiliation Shared Recourses, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Guillermo Rivas,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Garrett Larson,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Tibor A. Rauch,

Current address: Department of Orthopedic Surgery, Rush University Medical Center, Chicago, Illinois, United States of America

Affiliation Department of Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Gerd P. Pfeifer,

Affiliation Department of Molecular Medicine, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯
Piroska E. Szabó

* E-mail: pszabo@coh.org

Affiliation Department of Molecular and Cellular Biology, Beckman Research Institute, City of Hope National Medical Centre, Duarte, California, United States of America
⨯

CTCF-Dependent Chromatin Bias Constitutes Transient Epigenetic Memory of the Mother at the H19-Igf2 Imprinting Control Region in Prospermatogonia

Dong-Hoon Lee,
Purnima Singh,
Shirley Y. Tsai,
Nathan Oates,
Alexander Spalla,
Claudio Spalla,
Lucy Brown,
Guillermo Rivas,
Garrett Larson,
Tibor A. Rauch

Published: November 24, 2010
https://doi.org/10.1371/journal.pgen.1001224

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