The De Novo Cytosine Methyltransferase DRM2 Requires Intact UBA Domains and a Catalytically Mutated Paralog DRM3 during RNA–Directed DNA Methylation in Arabidopsis thaliana

• Ian R. Henderson,

  Affiliations Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America, Department of Plant Sciences, University of Cambridge, Cambridge, United Kingdom

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• Angelique Deleris,

  Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• William Wong,

  Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Xuehua Zhong,

  Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Hang Gyeong Chin,

  Affiliation New England Biolabs, Ipswich, Massachusetts, United States of America

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• Gregory A. Horwitz,

  Affiliation Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America

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• Krystyna A. Kelly,

  Affiliation Department of Plant Sciences, University of Cambridge, Cambridge, United Kingdom

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• Sriharsa Pradhan,

  Affiliation New England Biolabs, Ipswich, Massachusetts, United States of America

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• Steven E. Jacobsen

  * E-mail: jacobsen@ucla.edu

  Affiliations Department of Molecular, Cell, and Developmental Biology, University of California Los Angeles, Los Angeles, California, United States of America, Howard Hughes Medical Institute, University of California Los Angeles, Los Angeles, California, United States of America

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