CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

Michael P. Schnetz; Lusy Handoko; Batool Akhtar-Zaidi; Cynthia F. Bartels; C. Filipe Pereira; Amanda G. Fisher; David J. Adams; Paul Flicek; Gregory E. Crawford; Thomas LaFramboise; Paul Tesar; Chia-Lin Wei; Peter C. Scacheri

doi:10.1371/journal.pgen.1001023

Loading metrics

Open Access

Peer-reviewed

Research Article

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

Michael P. Schnetz ,

Contributed equally to this work with: Michael P. Schnetz, Lusy Handoko

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Lusy Handoko ,

Contributed equally to this work with: Michael P. Schnetz, Lusy Handoko

Affiliation Genome Technology and Biology Group, Genome Institute of Singapore, Singapore, Singapore
⨯
Batool Akhtar-Zaidi,

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Cynthia F. Bartels,

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
C. Filipe Pereira,

Affiliation Lymphocyte Development Group, Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
⨯
Amanda G. Fisher,

Affiliation Lymphocyte Development Group, Medical Research Council Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom
⨯
David J. Adams,

Affiliation Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Paul Flicek,

Affiliation European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom
⨯
Gregory E. Crawford,

Affiliation Institute for Genome Sciences & Policy and Department of Pediatrics, Duke University, Durham, North Carolina, United States of America
⨯
Thomas LaFramboise,

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Paul Tesar,

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯
Chia-Lin Wei,

Affiliations Genome Technology and Biology Group, Genome Institute of Singapore, Singapore, Singapore, Department of Biological Sciences, National University of Singapore, Singapore, Singapore
⨯
Peter C. Scacheri

* E-mail: peter.scacheri@case.edu

Affiliation Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
⨯

CHD7 Targets Active Gene Enhancer Elements to Modulate ES Cell-Specific Gene Expression

Michael P. Schnetz,
Lusy Handoko,
Batool Akhtar-Zaidi,
Cynthia F. Bartels,
C. Filipe Pereira,
Amanda G. Fisher,
David J. Adams,
Paul Flicek,
Gregory E. Crawford,
Thomas LaFramboise

Published: July 15, 2010
https://doi.org/10.1371/journal.pgen.1001023

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Enhancer elements
Is the Subject Area "Enhancer elements" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.
Cell binding
Is the Subject Area "Cell binding" applicable to this article?

Thanks for your feedback.
DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Heterozygosity
Is the Subject Area "Heterozygosity" applicable to this article?

Thanks for your feedback.
Gene regulation
Is the Subject Area "Gene regulation" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.