Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

Andrés Dekanty; Nuria M. Romero; Agustina P. Bertolin; María G. Thomas; Claudia C. Leishman; Joel I. Perez-Perri; Graciela L. Boccaccio; Pablo Wappner

doi:10.1371/journal.pgen.1000994

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Peer-reviewed

Research Article

Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

Andrés Dekanty,

Affiliation Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Nuria M. Romero,

Affiliations Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina, Departamento de Fisiología, Biología Molecular, y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Agustina P. Bertolin,

Affiliations Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
⨯
María G. Thomas,

Affiliations Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
⨯
Claudia C. Leishman,

Affiliation Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Joel I. Perez-Perri,

Affiliation Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina
⨯
Graciela L. Boccaccio,

Affiliations Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
⨯
Pablo Wappner

* E-mail: pwappner@leloir.org.ar

Affiliations Instituto Leloir, Universidad de Buenos Aires, Buenos Aires, Argentina, Departamento de Fisiología, Biología Molecular, y Celular, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina, Consejo Nacional de Investigaciones Científicas y Técnicas, Buenos Aires, Argentina
⨯

Drosophila Genome-Wide RNAi Screen Identifies Multiple Regulators of HIF–Dependent Transcription in Hypoxia

Andrés Dekanty,
Nuria M. Romero,
Agustina P. Bertolin,
María G. Thomas,
Claudia C. Leishman,
Joel I. Perez-Perri,
Graciela L. Boccaccio,
Pablo Wappner

Published: June 24, 2010
https://doi.org/10.1371/journal.pgen.1000994

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Hypoxia
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Genetic screens
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MicroRNAs
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Drosophila melanogaster
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Medical hypoxia
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