The Use of Orthologous Sequences to Predict the Impact of Amino Acid Substitutions on Protein Function

• Nicholas J. Marini ,

  Contributed equally to this work with: Nicholas J. Marini, Paul D. Thomas

  * E-mail: nmarini@berkeley.edu (NJM); pdthomas@usc.edu (PDT)

  Affiliation California Institute for Quantitative Biosciences, Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, California, United States of America

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• Paul D. Thomas ,

  Contributed equally to this work with: Nicholas J. Marini, Paul D. Thomas

  * E-mail: nmarini@berkeley.edu (NJM); pdthomas@usc.edu (PDT)

  Current address: Division of Bioinformatics, Department of Preventive Medicine, University of Southern California, Los Angeles, California, United States of America

  Affiliation Evolutionary Systems Biology Group, SRI International, Menlo Park, California, United States of America

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• Jasper Rine

  Affiliation California Institute for Quantitative Biosciences, Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, California, United States of America

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