Characterization of Oxidative Guanine Damage and Repair in Mammalian Telomeres

Zhilong Wang; David B. Rhee; Jian Lu; Christina T. Bohr; Fang Zhou; Haritha Vallabhaneni; Nadja C. de Souza-Pinto; Yie Liu

doi:10.1371/journal.pgen.1000951

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Peer-reviewed

Research Article

Characterization of Oxidative Guanine Damage and Repair in Mammalian Telomeres

Zhilong Wang,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
David B. Rhee,

Affiliations Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America, University of Tennessee–Oak Ridge National Laboratory Graduate School of Genome Science and Technology, Knoxville, Tennessee, United States of America
⨯
Jian Lu,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Christina T. Bohr,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Fang Zhou,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Haritha Vallabhaneni,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Nadja C. de Souza-Pinto,

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯
Yie Liu

* E-mail: liuyie@mail.nih.gov

Current address: NIH Biomedical Research Center, Baltimore, Maryland, United States of America

Affiliation Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
⨯

Characterization of Oxidative Guanine Damage and Repair in Mammalian Telomeres

Zhilong Wang,
David B. Rhee,
Jian Lu,
Christina T. Bohr,
Fang Zhou,
Haritha Vallabhaneni,
Nadja C. de Souza-Pinto,
Yie Liu

Published: May 13, 2010
https://doi.org/10.1371/journal.pgen.1000951

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Telomeres
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Guanine
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DNA damage
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DNA repair
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Bone marrow cells
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DNA-binding proteins
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Oxidative damage
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Oxidative stress
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