Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization

Silvia Kocanova; Elizabeth A. Kerr; Sehrish Rafique; Shelagh Boyle; Elad Katz; Stephanie Caze-Subra; Wendy A. Bickmore; Kerstin Bystricky

doi:10.1371/journal.pgen.1000922

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Peer-reviewed

Research Article

Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization

Silvia Kocanova ,

Contributed equally to this work with: Silvia Kocanova, Elizabeth A. Kerr

Affiliations Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse - UPS, Toulouse, France, LBME, CNRS, Toulouse, France
⨯
Elizabeth A. Kerr ,

Contributed equally to this work with: Silvia Kocanova, Elizabeth A. Kerr

Affiliations The Breakthrough Breast Cancer Research Unit, Edinburgh, United Kingdom, Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Sehrish Rafique,

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Shelagh Boyle,

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Elad Katz,

Affiliation The Breakthrough Breast Cancer Research Unit, Edinburgh, United Kingdom
⨯
Stephanie Caze-Subra,

Affiliations Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse - UPS, Toulouse, France, LBME, CNRS, Toulouse, France
⨯
Wendy A. Bickmore ,

* E-mail: W.Bickmore@hgu.mrc.ac.uk (WAB); kerstin.bystricky@biotoul.fr (KB)

Affiliation Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom
⨯
Kerstin Bystricky

* E-mail: W.Bickmore@hgu.mrc.ac.uk (WAB); kerstin.bystricky@biotoul.fr (KB)

Affiliations Laboratoire de Biologie Moléculaire Eucaryote, Université de Toulouse - UPS, Toulouse, France, LBME, CNRS, Toulouse, France
⨯

Activation of Estrogen-Responsive Genes Does Not Require Their Nuclear Co-Localization

Silvia Kocanova,
Elizabeth A. Kerr,
Sehrish Rafique,
Shelagh Boyle,
Elad Katz,
Stephanie Caze-Subra,
Wendy A. Bickmore,
Kerstin Bystricky

Published: April 22, 2010
https://doi.org/10.1371/journal.pgen.1000922

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Gene expression
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In situ hybridization
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Estrogens
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DNA transcription
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Breast cancer
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Epithelial cells
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Gene regulation
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