Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

Nausica Arnoult; Caroline Schluth-Bolard; Anne Letessier; Irena Drascovic; Rachida Bouarich-Bourimi; Judith Campisi; Sahn-ho Kim; Amina Boussouar; Alexandre Ottaviani; Frédérique Magdinier; Eric Gilson; Arturo Londoño-Vallejo

doi:10.1371/journal.pgen.1000920

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Peer-reviewed

Research Article

Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

Nausica Arnoult,

Affiliation Telomeres and Cancer Laboratory, Institut Curie, CNRS, UPMC University Paris 06, Paris, France
⨯
Caroline Schluth-Bolard,

Affiliation Epigenetics and Telomere Regulation, CNRS ENS UCBL IFR128, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Anne Letessier,

Affiliation Functional Organization and Plasticity of Mammalian Genomes, Institut Curie, UPMC University Paris 06, Paris, France
⨯
Irena Drascovic,

Affiliation Telomeres and Cancer Laboratory, Institut Curie, CNRS, UPMC University Paris 06, Paris, France
⨯
Rachida Bouarich-Bourimi,

Affiliation Telomeres and Cancer Laboratory, Institut Curie, CNRS, UPMC University Paris 06, Paris, France
⨯
Judith Campisi,

Affiliations Lawrence Berkeley Laboratory, Berkeley, California, United States of America, Buck Institute for Age Research, Novato, California, United States of America
⨯
Sahn-ho Kim,

Current address: Vattikuti Urology Institute, Henry Ford Health System, Detroit, Michigan, United States of America

Affiliation Lawrence Berkeley Laboratory, Berkeley, California, United States of America
⨯
Amina Boussouar,

Affiliation Epigenetics and Telomere Regulation, CNRS ENS UCBL IFR128, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Alexandre Ottaviani,

Affiliation Epigenetics and Telomere Regulation, CNRS ENS UCBL IFR128, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Frédérique Magdinier,

Affiliation Epigenetics and Telomere Regulation, CNRS ENS UCBL IFR128, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Eric Gilson,

Affiliation Epigenetics and Telomere Regulation, CNRS ENS UCBL IFR128, Ecole Normale Supérieure de Lyon, Lyon, France
⨯
Arturo Londoño-Vallejo

* E-mail: Arturo.Londono@curie.fr

Affiliation Telomeres and Cancer Laboratory, Institut Curie, CNRS, UPMC University Paris 06, Paris, France
⨯

Replication Timing of Human Telomeres Is Chromosome Arm–Specific, Influenced by Subtelomeric Structures and Connected to Nuclear Localization

Nausica Arnoult,
Caroline Schluth-Bolard,
Anne Letessier,
Irena Drascovic,
Rachida Bouarich-Bourimi,
Judith Campisi,
Sahn-ho Kim,
Amina Boussouar,
Alexandre Ottaviani,
Frédérique Magdinier

Published: April 22, 2010
https://doi.org/10.1371/journal.pgen.1000920

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Telomeres
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Synthesis phase
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Chromosomes
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DNA replication
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Arms
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