Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa

Peter L. Oliver; Leo Goodstadt; Joshua J. Bayes; Zoë Birtle; Kevin C. Roach; Nitin Phadnis; Scott A. Beatson; Gerton Lunter; Harmit S. Malik; Chris P. Ponting

doi:10.1371/journal.pgen.1000753

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Open Access

Peer-reviewed

Research Article

Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa

Peter L. Oliver ,

Contributed equally to this work with: Peter L. Oliver, Leo Goodstadt

Affiliation Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
⨯
Leo Goodstadt ,

Contributed equally to this work with: Peter L. Oliver, Leo Goodstadt

Affiliation Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
⨯
Joshua J. Bayes,

Affiliation Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, United States of America
⨯
Zoë Birtle,

Affiliation Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
⨯
Kevin C. Roach,

Affiliations Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America
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Nitin Phadnis,

Affiliation Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Scott A. Beatson,

Affiliation School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Queensland, Australia
⨯
Gerton Lunter,

Affiliation Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
⨯
Harmit S. Malik ,

* E-mail: chris.ponting@dpag.ox.ac.uk (CPP); hsmalik@fhcrc.org (HSM)

Affiliations Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
⨯
Chris P. Ponting

* E-mail: chris.ponting@dpag.ox.ac.uk (CPP); hsmalik@fhcrc.org (HSM)

Affiliation Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom
⨯

Accelerated Evolution of the Prdm9 Speciation Gene across Diverse Metazoan Taxa

Peter L. Oliver,
Leo Goodstadt,
Joshua J. Bayes,
Zoë Birtle,
Kevin C. Roach,
Nitin Phadnis,
Scott A. Beatson,
Gerton Lunter,
Harmit S. Malik,
Chris P. Ponting

Published: December 4, 2009
https://doi.org/10.1371/journal.pgen.1000753

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Evolutionary genetics
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Rodents
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Primates
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DNA-binding proteins
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Single nucleotide polymorphisms
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Sequence alignment
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