A Claudin-9–Based Ion Permeability Barrier Is Essential for Hearing

Yoko Nakano; Sung H. Kim; Hyoung-Mi Kim; Joel D. Sanneman; Yuzhou Zhang; Richard J. H. Smith; Daniel C. Marcus; Philine Wangemann; Randy A. Nessler; Botond Bánfi

doi:10.1371/journal.pgen.1000610

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Open Access

Peer-reviewed

Research Article

A Claudin-9–Based Ion Permeability Barrier Is Essential for Hearing

Yoko Nakano,

Affiliations Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, United States of America, Inflammation Program, University of Iowa, Coralville, Iowa, United States of America
⨯
Sung H. Kim,

Affiliation Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Hyoung-Mi Kim,

Affiliation Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Joel D. Sanneman,

Affiliation Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Yuzhou Zhang,

Affiliation Department of Otolaryngology – Head and Neck Surgery, University of Iowa, Iowa City, Iowa, United States of America
⨯
Richard J. H. Smith,

Affiliation Department of Otolaryngology – Head and Neck Surgery, University of Iowa, Iowa City, Iowa, United States of America
⨯
Daniel C. Marcus,

Affiliation Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Philine Wangemann,

Affiliation Department of Anatomy and Physiology, Kansas State University, Manhattan, Kansas, United States of America
⨯
Randy A. Nessler,

Affiliation Central Microscopy Research Facility, University of Iowa, Iowa City, Iowa, United States of America
⨯
Botond Bánfi

* E-mail: botond-banfi@uiowa.edu

Affiliations Department of Anatomy and Cell Biology, University of Iowa, Iowa City, Iowa, United States of America, Inflammation Program, University of Iowa, Coralville, Iowa, United States of America, Department of Otolaryngology – Head and Neck Surgery, University of Iowa, Iowa City, Iowa, United States of America, Department of Internal Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯

A Claudin-9–Based Ion Permeability Barrier Is Essential for Hearing

Yoko Nakano,
Sung H. Kim,
Hyoung-Mi Kim,
Joel D. Sanneman,
Yuzhou Zhang,
Richard J. H. Smith,
Daniel C. Marcus,
Philine Wangemann,
Randy A. Nessler,
Botond Bánfi

Published: August 21, 2009
https://doi.org/10.1371/journal.pgen.1000610

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