Mitochondrial 2,4-dienoyl-CoA Reductase Deficiency in Mice Results in Severe Hypoglycemia with Stress Intolerance and Unimpaired Ketogenesis

• Ilkka J. Miinalainen,

  Affiliation Department of Biochemistry and Biocenter Oulu, University of Oulu, Oulu, Finland

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• Werner Schmitz,

  Affiliation Theodor-Boveri-Institut für Biowissenschaften (Biozentrum) der Universität Würzburg, Würzburg, Germany

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• Anne Huotari,

  Affiliation Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, Kuopio, Finland

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• Kaija J. Autio,

  Affiliation Department of Biochemistry and Biocenter Oulu, University of Oulu, Oulu, Finland

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• Raija Soininen,

  Affiliation Department of Medical Biochemistry and Biocenter Oulu, University of Oulu, Oulu, Finland

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• Emiel Ver Loren van Themaat,

  Affiliation Bioinformatics Laboratory, Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands

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• Myriam Baes,

  Affiliation Laboratory of Cell Metabolism, Department of Pharmaceutical Sciences, Katholieke Universiteit Leuven, Leuven, Belgium

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• Karl-Heinz Herzig,

  Affiliations Department of Biotechnology and Molecular Medicine, A.I. Virtanen Institute for Molecular Sciences, Kuopio, Finland, Department of Internal Medicine, Kuopio and Institute of Biomedicine, Division of Physiology and Biocenter of Oulu, Oulu University Medical School, Oulu, Finland

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• Ernst Conzelmann,

  Affiliation Theodor-Boveri-Institut für Biowissenschaften (Biozentrum) der Universität Würzburg, Würzburg, Germany

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• J. Kalervo Hiltunen

  * E-mail: Kalervo.Hiltunen@oulu.fi

  Affiliation Department of Biochemistry and Biocenter Oulu, University of Oulu, Oulu, Finland

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