A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

Open Access

Peer-reviewed

Research Article

Bryan N. Howie,

Current address: Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom
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Peter Donnelly,

Affiliations Department of Statistics, University of Oxford, Oxford, United Kingdom, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, United Kingdom
⨯
Jonathan Marchini

* E-mail: marchini@stats.ox.ac.uk

Affiliation Department of Statistics, University of Oxford, Oxford, United Kingdom
⨯

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Single nucleotide polymorphisms
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Haplotypes
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Variant genotypes
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Genome-wide association studies
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Hidden Markov models
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Algorithms
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Computer software
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Heterozygosity
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