Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

Tao Cai; Hiroki Hirai; Tetsunari Fukushige; Ping Yu; Guofeng Zhang; Abner L. Notkins; Michael Krause

doi:10.1371/journal.pgen.1000447

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Peer-reviewed

Research Article

Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

Tao Cai ,

* E-mail: tcai@mail.nih.gov (TC); mwkrause@helix.nih.gov (MK)

Affiliation Experimental Medicine Section, Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Hiroki Hirai,

Affiliation Experimental Medicine Section, Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Tetsunari Fukushige,

Affiliation Section of Developmental Biology, Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Ping Yu,

Affiliation Protein-Nucleic Acid Interactions Section, Structural Biophysics Laboratory, National Cancer Institute (NCI)-Frederick, Frederick, Maryland, United States of America
⨯
Guofeng Zhang,

Affiliation Laboratory of Bioengineering and Physical Science, National Institute of Biomedical Imaging and Bioengineering (NIBIB), National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Abner L. Notkins,

Affiliation Experimental Medicine Section, Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research (NIDCR), National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Michael Krause

* E-mail: tcai@mail.nih.gov (TC); mwkrause@helix.nih.gov (MK)

Affiliation Section of Developmental Biology, Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, Maryland, United States of America
⨯

Loss of the Transcriptional Repressor PAG-3/Gfi-1 Results in Enhanced Neurosecretion that is Dependent on the Dense-Core Vesicle Membrane Protein IDA-1/IA-2

Tao Cai,
Hiroki Hirai,
Tetsunari Fukushige,
Ping Yu,
Guofeng Zhang,
Abner L. Notkins,
Michael Krause

Published: April 3, 2009
https://doi.org/10.1371/journal.pgen.1000447

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