IL2RA Genetic Heterogeneity in Multiple Sclerosis and Type 1 Diabetes Susceptibility and Soluble Interleukin-2 Receptor Production

• Lisa M. Maier ,

  Contributed equally to this work with: Lisa M. Maier, Christopher E. Lowe, John A. Todd, David A. Hafler

  Affiliations Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

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• Christopher E. Lowe ,

  Contributed equally to this work with: Lisa M. Maier, Christopher E. Lowe, John A. Todd, David A. Hafler

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• Jason Cooper,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• Kate Downes,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• David E. Anderson,

  Affiliation Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Christopher Severson,

  Affiliation Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

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• Pamela M. Clark,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• Brian Healy,

  Affiliations Biostatistics Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Neil Walker,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• Cristin Aubin,

  Affiliation Program in Medical and Population Genetics, Broad Institute, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

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• Jorge R. Oksenberg,

  Affiliation University of California San Francisco, San Francisco, California, United States of America

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• Stephen L. Hauser,

  Affiliation University of California San Francisco, San Francisco, California, United States of America

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• Alistair Compston,

  Affiliation Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom

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• Stephen Sawcer,

  Affiliation Department of Clinical Neurosciences, Addenbrooke's Hospital, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom

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• The International Multiple Sclerosis Genetics Consortium,
• Philip L. De Jager,

  Affiliations Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America, Harvard Medical School/Partners Healthcare Center for Genetics and Genomics, Boston, Massachusetts, United States of America

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• Linda S. Wicker,

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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• John A. Todd ,

  Contributed equally to this work with: Lisa M. Maier, Christopher E. Lowe, John A. Todd, David A. Hafler

  Affiliation Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory, Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

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•  [ ... ],
• David A. Hafler

  Contributed equally to this work with: Lisa M. Maier, Christopher E. Lowe, John A. Todd, David A. Hafler

  * E-mail: hafler@broad.mit.edu

  Affiliations Division of Molecular Immunology, Center for Neurologic Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America, Program in Medical and Population Genetics, Broad Institute, Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, United States of America

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