Genomewide Analysis of PRC1 and PRC2 Occupancy Identifies Two Classes of Bivalent Domains

• Manching Ku ,

  Contributed equally to this work with: Manching Ku, Richard P. Koche, Esther Rheinbay

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Richard P. Koche ,

  Contributed equally to this work with: Manching Ku, Richard P. Koche, Esther Rheinbay

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Division of Health Sciences and Technology, MIT, Cambridge, Massachusetts, United States of America

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• Esther Rheinbay ,

  Contributed equally to this work with: Manching Ku, Richard P. Koche, Esther Rheinbay

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Bioinformatics Program and Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America

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• Eric M. Mendenhall,

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Mitsuhiro Endoh,

  Affiliation RIKEN Research Center for Allergy and Immunology, Tsurumi-ku, Yokohama, Japan

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• Tarjei S. Mikkelsen,

  Affiliations Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Division of Health Sciences and Technology, MIT, Cambridge, Massachusetts, United States of America

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• Aviva Presser,

  Affiliations Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, United States of America

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• Chad Nusbaum,

  Affiliation Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Xiaohui Xie,

  Affiliation Department of Computer Science, University of California Irvine, Irvine, California, United States of America

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• Andrew S. Chi,

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Mazhar Adli,

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America

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• Simon Kasif,

  Affiliation Bioinformatics Program and Department of Biomedical Engineering, Boston University, Boston, Massachusetts, United States of America

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• Leon M. Ptaszek,

  Affiliations Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, United States of America, Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America, Stowers Medical Institute, Center for Regenerative Medicine, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Chad A. Cowan,

  Affiliations Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America, Stowers Medical Institute, Center for Regenerative Medicine, Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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• Eric S. Lander,

  Affiliations Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Whitehead Institute for Biomedical Research, MIT, Cambridge, Massachusetts, United States of America

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• Haruhiko Koseki,

  Affiliation RIKEN Research Center for Allergy and Immunology, Tsurumi-ku, Yokohama, Japan

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•  [ ... ],
• Bradley E. Bernstein

  * E-mail: Bernstein.Bradley@mgh.harvard.edu

  Affiliations Molecular Pathology Unit and Center for Cancer Research, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, United States of America, Harvard Stem Cell Institute, Cambridge, Massachusetts, United States of America

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