Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice

Rupert Öllinger; Andrew J. Childs; Hannah M. Burgess; Robert M. Speed; Pia R. Lundegaard; Nicola Reynolds; Nicola K. Gray; Howard J. Cooke; Ian R. Adams

doi:10.1371/journal.pgen.1000199

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Peer-reviewed

Research Article

Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice

Rupert Öllinger,

Affiliation MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
⨯
Andrew J. Childs,

Current address: MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen's Medical Research Institute, Edinburgh, United Kingdom

Affiliation MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
⨯
Hannah M. Burgess,

Affiliations MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom, School of Clinical Sciences and Community Health, University of Edinburgh, Edinburgh, United Kingdom, MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen's Medical Research Institute, Edinburgh, United Kingdom
⨯
Robert M. Speed,

Affiliation MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
⨯
Pia R. Lundegaard,

Affiliations MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom, Institute for Genetics and Molecular Medicine, Western General Hospital, Edinburgh, United Kingdom
⨯
Nicola Reynolds,

Current address: Wellcome Trust Centre for Stem Cell Research, Cambridge, United Kingdom

Affiliation MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
⨯
Nicola K. Gray,

Affiliations MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom, School of Clinical Sciences and Community Health, University of Edinburgh, Edinburgh, United Kingdom, MRC Human Reproductive Sciences Unit, Centre for Reproductive Biology, The Queen's Medical Research Institute, Edinburgh, United Kingdom
⨯
Howard J. Cooke ,

* E-mail: Howard.Cooke@hgu.mrc.ac.uk (HJC) (HC); Ian.Adams@hgu.mrc.ac.uk (IRA) (IA)

Affiliation MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom
⨯
Ian R. Adams

* E-mail: Howard.Cooke@hgu.mrc.ac.uk (HJC) (HC); Ian.Adams@hgu.mrc.ac.uk (IRA) (IA)

Affiliations MRC Human Genetics Unit, Western General Hospital, Edinburgh, United Kingdom, Edinburgh Cancer Research Centre, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom
⨯

Deletion of the Pluripotency-Associated Tex19.1 Gene Causes Activation of Endogenous Retroviruses and Defective Spermatogenesis in Mice

Rupert Öllinger,
Andrew J. Childs,
Hannah M. Burgess,
Robert M. Speed,
Pia R. Lundegaard,
Nicola Reynolds,
Nicola K. Gray,
Howard J. Cooke,
Ian R. Adams

Published: September 19, 2008
https://doi.org/10.1371/journal.pgen.1000199

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