Novel Roles for MLH3 Deficiency and TLE6-Like Amplification in DNA Mismatch Repair-Deficient Gastrointestinal Tumorigenesis and Progression

• Peng-Chieh Chen,

  Current address: Department of Genetics, Harvard Medical School, Harvard Partners Center for Genetics and Genomics, and Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

  Affiliations Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America, Department of Medicine, University of California Irvine, Irvine, California, United States of America

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• Mari Kuraguchi,

  Affiliations Department of Genetics, Harvard Medical School, Harvard Partners Center for Genetics and Genomics, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• John Velasquez,

  Affiliation Department of Medicine, University of California Irvine, Irvine, California, United States of America

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• Yuxun Wang,

  Affiliation Department of Molecular Genetics, Albert Einstein College of Medicine, New York, New York, United States of America

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• Kan Yang,

  Affiliation Strang Cancer Research Laboratory, Department of Medicine, Weill Medical College of Cornell University, New York, New York, United States of America

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• Robert Edwards,

  Affiliation Department of Pathology, University of California Irvine, Irvine, California, United States of America

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• Dan Gillen,

  Affiliation Department of Statistics, University of California Irvine, Irvine, California, United States of America

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• Winfried Edelmann,

  Affiliation Department of Molecular Genetics, Albert Einstein College of Medicine, New York, New York, United States of America

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• Raju Kucherlapati,

  Affiliations Department of Genetics, Harvard Medical School, Harvard Partners Center for Genetics and Genomics, Boston, Massachusetts, United States of America, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, United States of America

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• Steven M. Lipkin

  * E-mail: slipkin@uci.edu

  Affiliations Department of Biological Chemistry, University of California Irvine, Irvine, California, United States of America, Department of Medicine, University of California Irvine, Irvine, California, United States of America

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