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Open Access
Peer-reviewed
Research Article
CpG Island Methylation in a Mouse Model of Lymphoma Is Driven by the Genetic Configuration of Tumor Cells
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Rene Opavsky ,
Contributed equally to this work with: Rene Opavsky, Shu-Huei Wang
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Shu-Huei Wang ,
Contributed equally to this work with: Rene Opavsky, Shu-Huei Wang
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America , Department of Pathology, The Ohio State University, Columbus, Ohio, United States of America
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Prashant Trikha,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Aparna Raval,
¤ Current address: Department of Medicine, Stanford University, Stanford, California, United States of America
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
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Yuan Huang,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Yue-Zhong Wu,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Pathology, The Ohio State University, Columbus, Ohio, United States of America
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Benjamin Rodriguez,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Benjamin Keller,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Sandya Liyanarachchi,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
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Guo Wei,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
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Ramana V Davuluri,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America
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Michael Weinstein,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Dean Felsher,
Affiliation Department of Medicine, Stanford University, Stanford, California, United States of America
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Michael Ostrowski,
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, Ohio, United States of America
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Gustavo Leone ,
To whom correspondence should be addressed. E-mail: Gustavo.Leone@osumc.edu (GL); Christoph.Plass@osumc.edu (CP)
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Molecular Genetics, The Ohio State University, Columbus, Ohio, United States of America
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Christoph Plass
To whom correspondence should be addressed. E-mail: Gustavo.Leone@osumc.edu (GL); Christoph.Plass@osumc.edu (CP)
Affiliations Human Cancer Genetics Program, Department of Molecul\ar Virology, Immunology and Medical Genetics, The Ohio State University, Columbus, Ohio, United States of America , Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America , Department of Pathology, The Ohio State University, Columbus, Ohio, United States of America
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CpG Island Methylation in a Mouse Model of Lymphoma Is Driven by the Genetic Configuration of Tumor Cells
- Rene Opavsky,
- Shu-Huei Wang,
- Prashant Trikha,
- Aparna Raval,
- Yuan Huang,
- Yue-Zhong Wu,
- Benjamin Rodriguez,
- Benjamin Keller,
- Sandya Liyanarachchi,
- Guo Wei
![PLOS](/resource/img/logo-plos.png)
- Published: September 28, 2007
- https://doi.org/10.1371/journal.pgen.0030167