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Open Access
Peer-reviewed
Research Article
Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer
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Kornel E Schuebel ,
Contributed equally to this work with: Kornel E Schuebel, Wei Chen, Leslie Cope, Sabine C Glöckner
*To whom correspondence should be addressed. E-mail: kornels@jhmi.edu (KES); sbaylin@jhmi.edu (SBB)
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Wei Chen ,
Contributed equally to this work with: Kornel E Schuebel, Wei Chen, Leslie Cope, Sabine C Glöckner
Affiliations Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America, Predoctoral Training Program in Human Genetics, The Johns Hopkins University, Baltimore, Maryland, United States of America
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Leslie Cope ,
Contributed equally to this work with: Kornel E Schuebel, Wei Chen, Leslie Cope, Sabine C Glöckner
Affiliation Biometry and Clinical Trials Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Sabine C Glöckner ,
Contributed equally to this work with: Kornel E Schuebel, Wei Chen, Leslie Cope, Sabine C Glöckner
Affiliation Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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Hiromu Suzuki,
Affiliation First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
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Joo-Mi Yi,
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Timothy A Chan,
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Leander Van Neste,
Affiliation Department of Molecular Biotechnology, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium
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Wim Van Criekinge,
Affiliation Oncomethylome Sciences, Liege, Belgium
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Sandra van den Bosch,
Affiliation Department of Pathology, University of Maastricht, Maastricht, The Netherlands
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Manon van Engeland,
Affiliation Department of Pathology, University of Maastricht, Maastricht, The Netherlands
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Angela H Ting,
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Kamwing Jair,
Affiliation Bionumerik Pharmaceuticals Inc., San Antonio, Texas, United States of America
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Wayne Yu,
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Minoru Toyota,
Affiliation First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
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Kohzoh Imai,
Affiliation First Department of Internal Medicine, Sapporo Medical University, Sapporo, Japan
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Nita Ahuja,
Affiliation Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
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James G Herman,
Affiliation Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America
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Stephen B Baylin
*To whom correspondence should be addressed. E-mail: kornels@jhmi.edu (KES); sbaylin@jhmi.edu (SBB)
Affiliations Cancer Biology Division, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States of America, Predoctoral Training Program in Human Genetics, The Johns Hopkins University, Baltimore, Maryland, United States of America
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Comparing the DNA Hypermethylome with Gene Mutations in Human Colorectal Cancer
- Kornel E Schuebel,
- Wei Chen,
- Leslie Cope,
- Sabine C Glöckner,
- Hiromu Suzuki,
- Joo-Mi Yi,
- Timothy A Chan,
- Leander Van Neste,
- Wim Van Criekinge,
- Sandra van den Bosch
- Published: September 21, 2007
- https://doi.org/10.1371/journal.pgen.0030157