A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease

Timothy G Lesnick; Spiridon Papapetropoulos; Deborah C Mash; Jarlath Ffrench-Mullen; Lina Shehadeh; Mariza de Andrade; John R Henley; Walter A Rocca; J. Eric Ahlskog; Demetrius M Maraganore

doi:10.1371/journal.pgen.0030098

Loading metrics

Open Access

Peer-reviewed

Research Article

A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease

Timothy G Lesnick,

Affiliation Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Spiridon Papapetropoulos,

Affiliation Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
⨯
Deborah C Mash,

Affiliation Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
⨯
Jarlath Ffrench-Mullen,

Affiliation Gene Logic, Gaithersburg, Maryland, United States of America
⨯
Lina Shehadeh,

Affiliation Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
⨯
Mariza de Andrade,

Affiliation Division of Biostatistics, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
John R Henley,

Affiliation Department of Physiology and Biomedical Engineering, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Walter A Rocca,

Affiliations Division of Epidemiology, Department of Health Sciences Research, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America , Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
J. Eric Ahlskog,

Affiliation Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
Demetrius M Maraganore

*To whom correspondence should be addressed. E-mail: dmaraganore@mayo.edu

Affiliation Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯

A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease

Timothy G Lesnick,
Spiridon Papapetropoulos,
Deborah C Mash,
Jarlath Ffrench-Mullen,
Lina Shehadeh,
Mariza de Andrade,
John R Henley,
Walter A Rocca,
J. Eric Ahlskog,
Demetrius M Maraganore

Published: June 15, 2007
https://doi.org/10.1371/journal.pgen.0030098

Reader Comments (2)

Post a new comment on this article

1 Response

01 Apr 2008
03:11 GMT
Most Recent

on the predicted probability of PD susceptibility Posted by Xuebing on 24 Mar 2008 at 06:06 GMT

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Axon guidance
Is the Subject Area "Axon guidance" applicable to this article?

Thanks for your feedback.
Parkinson disease
Is the Subject Area "Parkinson disease" applicable to this article?

Thanks for your feedback.
Forecasting
Is the Subject Area "Forecasting" applicable to this article?

Thanks for your feedback.
Data mining
Is the Subject Area "Data mining" applicable to this article?

Thanks for your feedback.
Genetic predisposition
Is the Subject Area "Genetic predisposition" applicable to this article?

Thanks for your feedback.
Gene prediction
Is the Subject Area "Gene prediction" applicable to this article?

Thanks for your feedback.