Inducible and Reversible Clock Gene Expression in Brain Using the tTA System for the Study of Circadian Behavior

Hee-Kyung Hong; Jason L Chong; Weimin Song; Eun Joo Song; Amira A Jyawook; Andrew C Schook; Caroline H Ko; Joseph S Takahashi

doi:10.1371/journal.pgen.0030033

Loading metrics

Open Access

Peer-reviewed

Research Article

Inducible and Reversible Clock Gene Expression in Brain Using the tTA System for the Study of Circadian Behavior

Hee-Kyung Hong,

Affiliations Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America , Center for Functional Genomics, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Jason L Chong,

Affiliation Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Weimin Song,

Affiliations Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Eun Joo Song,

Affiliations Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Amira A Jyawook,

Affiliations Center for Functional Genomics, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Andrew C Schook,

Affiliations Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯
Caroline H Ko,

Affiliations Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America , Department of Psychology, University of Toronto, Toronto, Ontario, Canada
⨯
Joseph S Takahashi

*To whom correspondence should be addressed. E-mail: j-takahashi@northwestern.edu

Affiliations Howard Hughes Medical Institute, Northwestern University, Evanston, Illinois, United States of America , Center for Functional Genomics, Northwestern University, Evanston, Illinois, United States of America , Department of Neurobiology and Physiology, Northwestern University, Evanston, Illinois, United States of America
⨯

Inducible and Reversible Clock Gene Expression in Brain Using the tTA System for the Study of Circadian Behavior

Hee-Kyung Hong,
Jason L Chong,
Weimin Song,
Eun Joo Song,
Amira A Jyawook,
Andrew C Schook,
Caroline H Ko,
Joseph S Takahashi

Published: February 23, 2007
https://doi.org/10.1371/journal.pgen.0030033

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Genetically modified animals
Is the Subject Area "Genetically modified animals" applicable to this article?

Thanks for your feedback.
Circadian rhythms
Is the Subject Area "Circadian rhythms" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Circadian oscillators
Is the Subject Area "Circadian oscillators" applicable to this article?

Thanks for your feedback.
Light pulses
Is the Subject Area "Light pulses" applicable to this article?

Thanks for your feedback.
Chronobiology
Is the Subject Area "Chronobiology" applicable to this article?

Thanks for your feedback.
Animal behavior
Is the Subject Area "Animal behavior" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.